Reaction: PRMT6 methylates histone H2A arginine-30 (H2AR29)
- in pathway: RMTs methylate histone arginines
PRMT6 methylates histone H2A at arginine-30 (H2AR29). Dimethylation of H2AR29 is specifically enriched at genes repressed by PRMT6, indicating a role for this mark in gene silencing (Waldmann et al. 2011).
Reaction - small molecule participants:
AdoHcy [nucleoplasm]
AdoMet [nucleoplasm]
Reactome.org reaction link: R-HSA-5229203
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-5229203