Reaction: botC HC:LC binds GT1b on the target cell surface
- in pathway: Toxicity of botulinum toxin type C (botC)
The botulinum toxin type C disulfide-bonded heavy chain - light chain heterodimer (“dichain”) (botC HC:LC, encoded by the C. botulinum botC1 gene) binds two molecules of GT1b ganglioside on the plasma membrane of a human target cell (Karalewitz et al. 2012).
Reaction - small molecule participants:
GT1b [plasma membrane]
Reactome.org reaction link: R-HSA-5246506
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Reaction input - small molecules:
ganglioside GT1b
Reaction output - small molecules:
Reactome.org link: R-HSA-5246506