Reaction: MeSeOH is reduced to MeSeH by TXNRD1
- in pathway: Metabolism of ingested MeSeO2H into MeSeH
Thioredoxin reductase 1 (TXNRD1) homodimer is involved in the reduction of methylselenenic acid (MeSeOH) into methylselenol (MeSeH) (Gromer and Gross 2002).
Reaction - small molecule participants:
H2O [cytosol]
NADP+ [cytosol]
MeSeH [cytosol]
MeSeOH [cytosol]
H+ [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-5263614
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Reaction input - small molecules:
methylselenenic acid
hydron
NADPH(4-)
Reaction output - small molecules:
water
NADP(3-)
methylselenol
Reactome.org link: R-HSA-5263614