Reaction: MeSeO2H is reduced to MeSeOH by TXNRD1
- in pathway: Metabolism of ingested MeSeO2H into MeSeH
Thioredoxin reductase 1 (TXNRD1) homodimer is involved in the reduction of methylseleninic acid (MeSeO2H) into methylselenenic acid (MeSeOH) (Gromer and Gross 2002).
Reaction - small molecule participants:
MeSeOH [cytosol]
H2O [cytosol]
NADP+ [cytosol]
MeSeO2H [cytosol]
H+ [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-5263616
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Reaction input - small molecules:
methylseleninic acid
hydron
NADPH(4-)
Reaction output - small molecules:
methylselenenic acid
water
NADP(3-)
Reactome.org link: R-HSA-5263616