Reaction: GSSebGalNac is reduced and methylated to MeSebGalNac
- in pathway: Formation of selenosugars for excretion
1beta-glutathionylseleno-N-acetyl-D-galactosamine (GSSebGalNac) aka selenosugar A is converted into 1beta-methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) aka selenosugar B by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Kobayashi et al. 2002).
Reaction - small molecule participants:
GSH [cytosol]
MeSebGalNac [cytosol]
AdoHcy [cytosol]
AdoMet [cytosol]
GSSebGalNac [cytosol]
Reactome.org reaction link: R-HSA-5333608
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
1beta-glutathionylseleno-N-acetyl-D-galactosamine
Reaction output - small molecules:
glutathionate(1-)
1beta-methylseleno-N-acetyl-D-galactosamine
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-5333608