Reaction: RAB3IP stimulates nucleotide exchange on RAB8A

- in pathway: Anchoring of the basal body to the plasma membrane
RAB3IP is a GEF for RAB8A, the only RAB GTPase localized in the cilium. GTP-bound RAB8A may play a role in recruiting vesicles from the Golgi to the ciliary base and is required for cilia formation (Nachury et al, 2007; Yoshimura et al, 2007; reviewed in Reiter et al, 2012).
Reaction - small molecule participants:
GDP [cytosol]
GTP [cytosol]
Reactome.org reaction link: R-HSA-5617816

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Reaction input - small molecules:
GTP(4-)
ChEBI:37565
Reaction output - small molecules:
GDP(3-)
ChEBI:58189
Reactome.org link: R-HSA-5617816