Reaction: HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1
- in pathway: PIWI-interacting RNA (piRNA) biogenesis
As inferred from mouse homologs, HENMT1 transfers a methyl group from S-adenosylmethionine to the 2' hydroxyl group at the 3' end of piRNA bound to the PIWIL2 complex in the cytosol.
Reaction - small molecule participants:
AdoHcy [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-5629218
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-5629218