Reaction: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)
- in pathway: PKMTs methylate histone lysines
MECOM (KMT8E, PRDM3) and PRDM16 (KMT8F) are histone 3 lysine-10 (H3K9) methyltransferases responsible for cytoplasmic H3K9 mono-methylation.
Reaction - small molecule participants:
AdoHcy [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-5634802
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-5634802