Reaction: AKR1A1 reduces D-glucuronate to L-gulonate
- in pathway: Formation of xylulose-5-phosphate
Cytosolic AKR1A1 (Aldo-keto reductase family 1 member A1) catalyzes the reduction by NADPH of D-glucuronate to L-gulonate (Barski et al. 1995).
Reaction - small molecule participants:
NADP+ [cytosol]
L-gulonate [cytosol]
H+ [cytosol]
D-glucuronate [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-5661256
======
Reaction input - small molecules:
hydron
D-glucuronate
NADPH(4-)
Reaction output - small molecules:
NADP(3-)
L-gulonate
Reactome.org link: R-HSA-5661256