Reaction: THG1L transfers GMP to 5' end of tRNA(His)
- in pathway: tRNA modification in the nucleus and cytosol
THG1L (THG1) adds a guanosine triphosphate residue to the 5' end of tRNA(His), a 3'-5' addition that contrasts with the usual 5'-3' directionality of nucleotide polymerases (Hyde et al. 2010).
Reaction - small molecule participants:
PPi [cytosol]
GTP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-6782434
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Reaction input - small molecules:
GTP(4-)
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
Reactome.org link: R-HSA-6782434