Reaction: TRMT11:TRMT112 methylates guanosine-10 in tRNA
- in pathway: tRNA modification in the nucleus and cytosol
As inferred from homologues in Saccharomyces cerevisiae, TRMT11 (catalytic subunit) and TRMT112 (zinc-binding subunit) form a complex which methylates the 2 position of guanosine-10 in tRNA (Purushothaman et al. 2005).
Reaction - small molecule participants:
AdoHcy [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-6786501
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-6786501