Reaction: TRMT44 2'-O-methylates uridine-44 in tRNA(Ser)
- in pathway: tRNA modification in the nucleus and cytosol
As inferred from the yeast homolog, TRMT44 methylates the 2' hydroxyl group of uridine-44 in tRNA(Ser). In yeast 2'-O-methyluridine-44 together with N(4)-acetylcytidine appears to be required to maintain abundance of tRNA(Ser).
Reaction - small molecule participants:
AdoHcy [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-6788707
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-6788707