Reaction: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC
- in pathway: Glyoxylate metabolism and glycine degradation
Cytosolic glycine N-methyltransferase (GNMT) catalyses the transfer of a methyl group from S-adenosylmethionine (AdoMet) to glycine (Gly) to form sarcosine (SARC, aka N-methylglycine) with the concomitant production of S-adenosylhomocysteine (AdoHcy) (Pakhomova et al. 2004).
Reaction - small molecule participants:
SARC [cytosol]
AdoHcy [cytosol]
AdoMet [cytosol]
Gly [cytosol]
Reactome.org reaction link: R-HSA-6798317
======
Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
glycine zwitterion
Reaction output - small molecules:
sarcosine zwitterion
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-6798317