Reaction: DHCR24 reduces ZYMOL to ZYMSTNL
- in pathway: Cholesterol biosynthesis via lathosterol
DHCR24 (delta(24)-sterol reductase) associated with the endoplasmic reticulum membranecatalyzes the reduction of ZYMOL (zymosterol) to ZYMSTNL (zymostenol) (Kandutsch & Russell 1960; Mitsche et al. 2015; Waterham et al. 2001).
Reaction - small molecule participants:
ZYMSTNL [endoplasmic reticulum membrane]
NADP+ [cytosol]
H+ [cytosol]
NADPH [cytosol]
ZYMOL [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-6807064
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Reaction input - small molecules:
hydron
NADPH(4-)
zymosterol
Reaction output - small molecules:
5alpha-cholest-8-en-3beta-ol
NADP(3-)
Reactome.org link: R-HSA-6807064