Reaction: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin
- in pathway: DNA replication initiation
At the beginning of this reaction, 1 molecule of 'dTTP', 1 molecule of 'dGTP', 1 molecule of 'dATP', 1 molecule of 'RNA primer:origin duplex:DNA polymerase alpha:primase complex', and 1 molecule of 'dCTP' are present. At the end of this reaction, 1 molecule of 'RNA primer-DNA primer:origin duplex' is present.
This reaction takes place in the 'nucleus' and is mediated by the 'DNA-directed DNA polymerase activity' of 'DNA polymerase alpha:primase'.
This reaction takes place in the 'nucleus' and is mediated by the 'DNA-directed DNA polymerase activity' of 'DNA polymerase alpha:primase'.
Reaction - small molecule participants:
dTTP [nucleoplasm]
dCTP [nucleoplasm]
dGTP [nucleoplasm]
dATP [nucleoplasm]
Reactome.org reaction link: R-HSA-68950
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Reaction input - small molecules:
dTTP(4-)
dCTP(4-)
dGTP(4-)
dATP(4-)
Reaction output - small molecules:
Reactome.org link: R-HSA-68950