Molecule: dATP(4-)

A 2'-deoxyribonucleoside 5'-triphosphate(4-) that is the tetraanion of 2'-deoxyadenosine 5'-triphosphate (dATP), arising from deprotonation of the four triphosphate OH groups; major species at pH 7.3.
Synonyms for dATP(4-) :
2'-deoxyadenosine 5'-triphosphate
2'-deoxyadenosine 5'-triphosphate tetraanion
2'-deoxyadenosine 5'-triphosphate(4-)
dATP
dATP tetraanion
Molecular Formula: C10H12N5O12P3
Molecular wt: 487.14990 g/mole
Charge: -4
SMILES: Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)O1
InChIKey: SUYVUBYJARFZHO-RRKCRQDMSA-J
InChI=1S/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/p-4/t5-,6+,7+/m0/s1
CHEBI:61404
Sample reactions for this molecule:
Insertion of correct bases opposite the lesion by POLH
D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate
Elongation Of The Telomeric Chromosome End
Elongation of Extended Telomeric Chromosome End
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere
Formation of C-strand Okazaki fragments
DNA polymerase delta polymerizes DNA across single stranded gap
DNA polymerase delta polymerizes DNA across single stranded gap
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin
Decitabine triphosphate incorporates into DNA