Reaction: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+

- in pathway: Phenylalanine metabolism
Cytosolic dihydropteridine reductase (QDPR) catalyzes the reaction of q-dihydrobiopterin with NADH + H+to form tetrahydrobiopterin and NAD+. The enzyme is a homodimer (Lockyer et al. 1987; Su et al. 1993).
Reaction - small molecule participants:
BH4 [cytosol]
NAD+ [cytosol]
H+ [cytosol]
qDHB [cytosol]
NADH [cytosol]
Reactome.org reaction link: R-HSA-71130

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Reaction input - small molecules:
hydron
ChEBI:15378
6,7-dihydrobiopterin
ChEBI:20680
NADH(2-)
ChEBI:57945
Reaction output - small molecules:
5,6,7,8-tetrahydrobiopterin
ChEBI:15372
NAD(1-)
ChEBI:57540
Reactome.org link: R-HSA-71130