Reaction: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine
- in pathway: Creatine metabolism
Cytosolic guanidinoacetate methyltransferase catalyzes the reaction of S-adenosylmethionine and guanidinoacetate to form S-adenosylhomocysteine and creatine (Stockler et al. 1996).
Reaction - small molecule participants:
CRET [cytosol]
H+ [cytosol]
AdoHcy [cytosol]
AdoMet [cytosol]
GAA [cytosol]
Reactome.org reaction link: R-HSA-71286
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
guanidinoacetic acid
Reaction output - small molecules:
creatine zwitterion
hydron
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-71286