Reaction: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+
- in pathway: TP53 Regulates Metabolic Genes
Cytosolic thioredoxin reductase catalyzes the reaction of thioredoxin, oxidized and NADPH + H+ to form thioredoxin, reduced and NADP+ (Urig et al. 2006).
Reaction - small molecule participants:
NADP+ [cytosol]
H+ [cytosol]
NADPH [cytosol]
NADP+ [cytosol]
H+ [cytosol]
NADPH [cytosol]
NADP+ [cytosol]
H+ [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-73646
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Reaction input - small molecules:
hydron
NADPH(4-)
hydron
NADPH(4-)
hydron
NADPH(4-)
Reaction output - small molecules:
NADP(3-)
NADP(3-)
NADP(3-)
Reactome.org link: R-HSA-73646