Reaction: SETD6 methylates RELA in the NFkB complex
- in pathway: PKMTs methylate histone lysines
SET domain containing 6 (SETD6) is an N-lysine methyltransferase that monomethylates the RelA subunit of nuclear factor kappa B (NF-kB) at Lys-310 (Levy et al. 2011, Chang et al. 2011).
Reaction - small molecule participants:
AdoHcy [nucleoplasm]
AdoMet [nucleoplasm]
Reactome.org reaction link: R-HSA-8865237
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-8865237