Reaction: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP
- in pathway: Protein methylation
Protein N-lysine methyltransferase METTL21D (VCPKMT) trimethylates lysine-315 of VCP (Kernstock et al. 2012, Cloutier et al. 2013).
Reaction - small molecule participants:
AdoHcy [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-8932276
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-8932276