Reaction: MCAT transfers Mal from Mal-CoA to NDUFAB1
- in pathway: Mitochondrial Fatty Acid Beta-Oxidation
The ACP (acyl carrier protein) NDUFAB1 is the cofactor protein that covalently binds all fatty acyl intermediates via a phosphopantetheine linkage during the synthesis of fatty acids. Mitochondrial malonyl-CoA-acyl carrier protein transacylase (MCAT, MT) catalyses the transfer of a malonyl moiety from malonyl-CoA (Mal-CoA) to the free thiol group of the phosphopantetheine arm of NDUFAB1, suggesting a possible role in fatty acid biosynthesis in the mitochondrion (Zhang et al. 2003).
Reaction - small molecule participants:
CoA-SH [mitochondrial matrix]
Malonyl-CoA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-8933547
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Reaction input - small molecules:
malonyl-CoA(5-)
Reaction output - small molecules:
coenzyme A(4-)
Reactome.org link: R-HSA-8933547