Reaction: Fe3+ dissociates from holoTF:TFRC dimer
- in pathway: Transferrin endocytosis and recycling
When endosomal pH reaches 6,0, protons replace the iron ions in the transferrin/receptor complex (Hemadi et al, 2006).
Reaction - small molecule participants:
Fe3+ [endosome lumen]
Reactome.org reaction link: R-HSA-917835
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Reaction input - small molecules:
Reaction output - small molecules:
iron(3+)
Reactome.org link: R-HSA-917835