Reaction: SPNS2 transports S1P from cytosol to extracellular region
- in pathway: Sphingolipid de novo biosynthesis
Sphingosine 1-phosphate (S1P) is a signaling molecule that regulates many physiological processes in development and the immune system. S1P is produced inside cells so must be secreted to exert its effects through its receptors. Protein spinster homolog 2 (SPNS2) is a S1P transporter involved in S1P secretion and regulation of its levels (Nagahashi et al. 2013).
Reaction - small molecule participants:
S1P [extracellular region]
S1P [cytosol]
Reactome.org reaction link: R-HSA-9695890
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Reaction input - small molecules:
sphingosine 1-phosphate(1-)
Reaction output - small molecules:
sphingosine 1-phosphate(1-)
Reactome.org link: R-HSA-9695890