Reaction: GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13
- in pathway: Olfactory Signaling Pathway
Olfactory receptors are associated with trimeric G protein complexes containing the GNAL (Golf, G alpha olf) alpha subunit, the GNB1 beta subunit, and the GNG13 gamma subunit. The binding of an odorant to an olfactory receptor causes the GNAL subunit to exchange GDP for GTP (Borgmann-Winter et al. 2016, and inferred from rat homologs). GNAL is a member of the Gs family of G alpha proteins.
Reaction - small molecule participants:
GDP [cytosol]
GTP [cytosol]
Reactome.org reaction link: R-HSA-9712201
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Reaction input - small molecules:
GTP(4-)
Reaction output - small molecules:
GDP(3-)
Reactome.org link: R-HSA-9712201