Reaction: GGPS1 hexamer transfers IPPP to GPP
- in pathway: Cholesterol biosynthesis
Further condensation of an isopentenyl pyrophosphate (IPPP) with geranyl pyrophosphate (GPP) to form farnesyl pyrophosphate (FAPP) is catalyzed by the prenyltransferases FPP synthase and GGPP synthase (Kavanagh et al, 2006).
Reaction - small molecule participants:
PPi [cytosol]
FAPP [cytosol]
GPP [cytosol]
IPPP [cytosol]
Reactome.org reaction link: R-HSA-9717830
======
Reaction input - small molecules:
geranyl diphosphate
isopentenyl diphosphate
Reaction output - small molecules:
diphosphate(3-)
2-trans,6-trans-farnesyl diphosphate
Reactome.org link: R-HSA-9717830