Reaction: GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13
Binding of a bitter tastant to the bitter taste receptor (TAS2R) causes a change in conformation that causes the Galpha subunit (GNAT3, gustducin) of the associated heterotrimeric G protein complex to exchange GDP for GTP (inferred from rat, mouse, and bovine homologs).
Reaction - small molecule participants:
GDP [cytosol]
GTP [cytosol]
Reactome.org reaction link: R-HSA-9728747
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Reaction input - small molecules:
GTP(4-)
Reaction output - small molecules:
GDP(3-)
Reactome.org link: R-HSA-9728747