Reaction: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA
- in pathway: Serine biosynthesis
The amino group needed for serine biosynthesis comes from glutamate (L-Glu). Its transfer onto 3-phosphonooxpyruvate (3POPA) is catalysed by PSAT1 dimer which needs pyridoxal phosphate (PXLP) as cofactor. (Baek et al. 2003)
Reaction - small molecule participants:
2OG [cytosol]
O-P-Ser [cytosol]
3POPA [cytosol]
L-Glu [cytosol]
Reactome.org reaction link: R-HSA-977333
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Reaction input - small molecules:
3-phosphonooxypyruvic acid
L-glutamate(1-)
Reaction output - small molecules:
2-oxoglutarate(2-)
O-phospho-L-serine
Reactome.org link: R-HSA-977333