Molecule: (20R,22R)-20,22-dihydroxycholesterol

An oxysterol that is cholesterol substituted by hydroxy groups at positions 20 and 22 (the 20R,22R-stereoisomer).
Synonyms for (20R,22R)-20,22-dihydroxycholesterol :
(20R,22R)-20,22-Dihydroxycholesterol
(20R,22R)-20,22-dihydroxycholesterol
(22R)-20alpha,22-Dihydroxycholesterol
20,22-Dihydroxycholesterol
20alpha,22R-Dihydroxycholesterol
20alpha,22beta-Dihydroxycholesterol
Molecular Formula: C27H46O3
Molecular wt: 418.65234 g/mole
Charge: 0
SMILES: [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@@](C)(O)[C@H](O)CCC(C)C
InChIKey: ISBSSBGEYIBVTO-TYKWNDPBSA-N
InChI=1S/C27H46O3/c1-17(2)6-11-24(29)27(5,30)23-10-9-21-20-8-7-18-16-19(28)12-14-25(18,3)22(20)13-15-26(21,23)4/h7,17,19-24,28-30H,6,8-16H2,1-5H3/t19-,20-,21-,22-,23-,24+,25-,26-,27+/m0/s1
CHEBI:1294
Sample reactions for this molecule:
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol
CYP11A1 cleaves 20a,22b-DHCHOL
CYP11A1 cleaves 20a,22b-DHCHOL
Defective CYP11A1 does not cleave 20a,22b-DHCHOL