Molecule: 11-deoxycorticosterone

A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.
Synonyms for 11-deoxycorticosterone :
11-Deoxycorticosterone
21-Hydroxy-4-pregnene-3,20-dione
21-hydroxyprogesterone
4-pregnen-21-ol-3,20-dione
Cortexone
DESOXYCORTICOSTERONE
DOC
Deoxycorticosterone
Desoxycortone
Kendall's desoxy compound B
Reichstein's substance Q
desoxycortone
Molecular Formula: C21H30O3
Molecular wt: 330.46110 g/mole
Charge: 0
SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)CO
InChIKey: ZESRJSPZRDMNHY-YFWFAHHUSA-N
InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1
CHEBI:16973
Desoxycorticosterone
Sample reactions for this molecule:
CYP21A2 21-hydroxylates PROG
CYP21A2 21-hydroxylates PROG
11DCORST translocates from cytosol to mitochondrial matrix
11DCORST translocates from cytosol to mitochondrial matrix
CYP11B2 oxidises 11DCORST to CORST
CYP11B2 oxidises 11DCORST to CORST
Defective CYP11B2 does not oxidise 11DCORST