Molecule: calcidiol

A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3.
Synonyms for calcidiol :
(3S,5Z,7E)-9,10-secocholesta-5,7,10-triene-3,25-diol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol
25(OH)D3
25-Hydroxyvitamin D3
25-hydroxycholecalciferol
25-hydroxyvitamin D3
3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL
Calcidiol
Calcifediol
Calcifediol anhydrous
calcidiol
Molecular Formula: C27H44O2
Molecular wt: 400.63706 g/mole
Charge: 0
SMILES: [H][C@@]1(CC[C@]2([H])[C@]1(C)CCC\C2=C/C=C1/C[C@@H](O)CCC1=C)[C@H](C)CCCC(C)(C)O
InChIKey: JWUBBDSIWDLEOM-DTOXIADCSA-N
InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
CHEBI:17933
Calcifediol
Sample reactions for this molecule:
25(OH)D translocates from lysosomal lumen to cytosol
25(OH)D translocates from lysosomal lumen to cytosol
CYP2R1 25-hydroxylates VD3 to 25(OH)D
CYP2R1 25-hydroxylates VD3 to 25(OH)D
CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D
CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D
25(OH)D binds GC
Defective CYP27B1 does not hydroxylate CDL
25(OH)D translocates from ER membrane to extracellular region
25(OH)D translocates from ER membrane to extracellular region