Reaction: PLC gamma 2-mediated PIP2 hydrolysis
- in pathway: GPVI-mediated activation cascade
At the beginning of this reaction, 1 molecule of '1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate' is present. At the end of this reaction, 1 molecule of '1D-myo-Inositol 1,4,5-trisphosphate', and 1 molecule of '1,2-Diacylglycerol' are present.
This reaction is mediated by the 'phospholipase C activity' of 'Phosphorylated phospholipase C gamma 2'.
This reaction is mediated by the 'phospholipase C activity' of 'Phosphorylated phospholipase C gamma 2'.
Reaction - small molecule participants:
I(1,4,5)P3 [cytosol]
DAG [plasma membrane]
PI(4,5)P2 [plasma membrane]
Reactome.org reaction link: R-HSA-114689
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Reaction input - small molecules:
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-)
Reaction output - small molecules:
1D-myo-inositol 1,4,5-trisphosphate(6-)
1,2-diacyl-sn-glycerol
Reactome.org link: R-HSA-114689