Molecule: 1D-myo-inositol 1,4,5-trisphosphate(6-)

Hexaanion of 1D-myo-inositol 1,4,5-trisphosphate arising from glabal deprotonation of the phosphate OH groups; major species at pH 7.3.
Synonyms for 1D-myo-inositol 1,4,5-trisphosphate(6-) :
1D-myo-inositol 1,4,5-triphosphate hexaanion
1D-myo-inositol 1,4,5-triphosphate(6-)
1D-myo-inositol 1,4,5-trisphosphate
1D-myo-inositol 1,4,5-trisphosphate hexaanion
Molecular Formula: C6H9O15P3
Molecular wt: 414.04790 g/mole
Charge: -6
SMILES: O[C@@H]1[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](O)[C@@H]1OP([O-])([O-])=O
InChIKey: MMWCIQZXVOZEGG-XJTPDSDZSA-H
InChI=1S/C6H15O15P3/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/p-6/t1-,2+,3+,4-,5-,6-/m1/s1
CHEBI:203600
Sample reactions for this molecule:
BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate
PIP2 hydrolysis
PLC gamma 2-mediated PIP2 hydrolysis
Binding of IP3 to IP3 receptor
Active PLCG1 hydrolyses PIP2
Active PLCG1 hydrolyses PIP2
Active PLCG1 hydrolyses PIP2
IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel
IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel
IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel