Reaction: DHDB is methylated to MHDB by COQ3
- in pathway: Ubiquinol biosynthesis
Mitochondrial COQ3 is an O-methyltransferase required in the reaction to convert 3,4-dihydroxy-5-decaprenylbenzoic acid (DHDB) to 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid (MHDB) (Jonassen & Clarke 2000).
Reaction - small molecule participants:
AdoHcy [mitochondrial matrix]
H+ [mitochondrial matrix]
MHDB [mitochondrial matrix]
AdoMet [mitochondrial matrix]
DHDB [mitochondrial matrix]
Reactome.org reaction link: R-HSA-2162193
======
Reaction input - small molecules:
S-adenosyl-L-methionine
3-decaprenyl-4,5-dihydroxybenzoic acid
Reaction output - small molecules:
S-adenosyl-L-homocysteine
hydron
3-decaprenyl-4-hydroxy-5-methoxybenzoic acid
Reactome.org link: R-HSA-2162193