Molecule: S-adenosyl-L-homocysteine

An organic sulfide that is the S-adenosyl derivative of L-homocysteine.
Synonyms for S-adenosyl-L-homocysteine :
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid
2-S-adenosyl-L-homocysteine
Adenosyl-L-homocysteine
AdoHcy
S-(5'-adenosyl)-L-homocysteine
S-ADENOSYL-L-HOMOCYSTEINE
S-Adenosyl-L-homocysteine
S-Adenosylhomocysteine
S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl]-L-homocysteine
SAH
adenosylhomocysteine
Molecular Formula: C14H20N6O5S
Molecular wt: 384.41204 g/mole
Charge: 0
SMILES: N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O
InChIKey: ZJUKTBDSGOFHSH-WFMPWKQPSA-N
InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1
CHEBI:16680
S-Adenosyl-L-homocysteine
Sample reactions for this molecule:
DeMQ10H2 is methylated to Q10H2 by COQ3
MDMQ10H2 is methylated to DMQ10H2 by COQ5
DHDB is methylated to MHDB by COQ3
TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe)
LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe)
LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe)
LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe)
KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine
TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58
TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9