Reaction: TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe)
- in pathway: Synthesis of wybutosine at G37 of tRNA(Phe)
As inferred from homologs in Saccharomyces cerevisiae, TYW3 transfers a methyl group from S-adenosylmethionine to yW-86 (7-((3S)-(3-amino-3-carboxypropyl))-4-demethylwyosine) at nucleotide 37 of tRNA(Phe), yielding yW-72 (7-((3S)-(3-amino-3-carboxypropyl))wyosine) and S-adenosylhomocysteine.
Reaction - small molecule participants:
AdoHcy [cytoplasm]
AdoMet [cytoplasm]
Reactome.org reaction link: R-HSA-6782879
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Reaction input - small molecules:
S-adenosyl-L-methionine
Reaction output - small molecules:
S-adenosyl-L-homocysteine
Reactome.org link: R-HSA-6782879