Molecule: S-adenosyl-L-methionine

A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine.
Synonyms for S-adenosyl-L-methionine :
(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine, inner salt
Acylcarnitine
AdoMet
S-(5'-deoxyadenosin-5'-yl)-L-methionine
S-Adenosyl-L-methionine
S-Adenosylmethionine
S-adenosyl-L-methionine
S-adenosylmethionine
SAM
SAMe
[1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl][(3S)-3-amino-3-carboxypropyl](methyl)sulfonium
Molecular Formula: C15H23N6O5S
Molecular wt: 399.44500 g/mole
Charge: +1
SMILES: C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-O
InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1
CHEBI:15414
S-Adenosyl_methionine
Sample reactions for this molecule:
DeMQ10H2 is methylated to Q10H2 by COQ3
MDMQ10H2 is methylated to DMQ10H2 by COQ5
DHDB is methylated to MHDB by COQ3
TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe)
LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe)
LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe)
TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe)
TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)
LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe)
KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine