Reaction: LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe)
- in pathway: Synthesis of wybutosine at G37 of tRNA(Phe)
As inferred from homologues in Saccharomyces cerevisiae, LCMT2 (TYW4) transfers a methyl group from S-adenosylmethionine to yW-72 (7-((3S)-3-amino-3-carboxypropyl)wyosine) at nucleotide 37 of tRNA(Phe), yielding yW-58 (7-((3S)-3-amino-3-(methoxycarbonyl)propyl)wyosine) and S-adenosylhomocysteine.
Reaction - small molecule participants:
AdoHcy [cytoplasm]
AdoMet [cytoplasm]
Reactome.org reaction link: R-HSA-6782881
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Reaction input - small molecules:
S-adenosyl-L-methionine
Reaction output - small molecules:
S-adenosyl-L-homocysteine
Reactome.org link: R-HSA-6782881