Reaction: LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe)
- in pathway: Synthesis of wybutosine at G37 of tRNA(Phe)
As inferred from homologues in Saccharomyces cerevisiae, LCMT2 (TYW4) methoxycarbonylates yW-58 (7-((3S)-3-amino-3-(methoxycarbonyl)propyl)wyosine) at nucleotide 37 of tRNA(Phe) yielding yW (wybutosine). A molecule of carbon dioxide is incorporated during the reaction.
Reaction - small molecule participants:
AdoHcy [cytoplasm]
CO2 [cytoplasm]
AdoMet [cytoplasm]
Reactome.org reaction link: R-HSA-6782890
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Reaction input - small molecules:
carbon dioxide
S-adenosyl-L-methionine
Reaction output - small molecules:
S-adenosyl-L-homocysteine
Reactome.org link: R-HSA-6782890