Reaction: TRMT13 2'-O-methylates adenosine-4 in tRNA
- in pathway: tRNA modification in the nucleus and cytosol
As inferred from the yeast homolog, TRMT13 methylates the 2' hydroxyl group of adenosine-4 in the acceptor stems of tRNA(His). The subcellular location of the reaction is unknown. Yeast lacking TRM13 do not have an obvious growth defect.
Reaction - small molecule participants:
AdoHcy [cytoplasm]
AdoMet [cytoplasm]
Reactome.org reaction link: R-HSA-6788668
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Reaction input - small molecules:
S-adenosyl-L-methionine
Reaction output - small molecules:
S-adenosyl-L-homocysteine
Reactome.org link: R-HSA-6788668