Molecule: progesterone

A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Synonyms for progesterone :
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
17alpha-progesterone
4-Pregnene-3,20-dione
Agolutin
Akrolutin
Crinone
Delta(4)-pregnene-3,20-dione
Gelbkoerperhormon
PROGESTERONE
Progesteron
Progesterone
corpus luteum hormone
luteohormone
progesterone
Molecular Formula: C21H30O2
Molecular wt: 314.46170 g/mole
Charge: 0
SMILES: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O
InChIKey: RJKFOVLPORLFTN-LEKSSAKUSA-N
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
CHEBI:17026
Progesterone
Sample reactions for this molecule:
Pregn-5-ene-3,20-dione isomerizes to progesterone
CYP17A1 17-hydroxylates P4 to 17aHPROG
CYP21A2 21-hydroxylates PROG
CYP21A2 21-hydroxylates PROG
Progesterone Activation Of CatSper
Defective CYP21A2 does not 21-hydroxylate PROG
Defective CYP17A1 does not 17-hydroxylate P4
P4 bind PGR (in the HSP90 chaperone complex)