Molecule: 25-hydroxycholesterol

Synonyms for 25-hydroxycholesterol :
25-Hydroxycholesterol
25-hydroxycholesterol
5-Cholestene-3beta,25-diol
Cholest-5-ene-3beta,25-diol
Molecular Formula: C27H46O2
Molecular wt: 402.65294 g/mole
Charge: 0
SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O
InChIKey: INBGSXNNRGWLJU-ZHHJOTBYSA-N
InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1
CHEBI:42977
Sample reactions for this molecule:
Cholesterol is hydroxylated to 25-hydroxycholesterol
CYP7B1 7-hydroxylates 25OH-CHOL
CYP7B1 7-hydroxylates 25OH-CHOL
Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL
OSBPs transport 25OH-CHOL from ER membrane to plasma membrane
OSBPs transport 25OH-CHOL from ER membrane to plasma membrane
OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane
OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane