Molecule: 10-formyltetrahydrofolate(2-)

Dianion of 10-formyltetrahydrofolic acid arising from deprotonation of both carboxylic acid functions.
Synonyms for 10-formyltetrahydrofolate(2-) :
10-HCO-H4folate
10-formyltetrahydrofolate
10-formyltetrahydrofolate dianion
Molecular Formula: C20H21N7O7
Molecular wt: 471.431 g/mole
Charge: -2
SMILES: [H]C(=O)N(CC1CNC2=C(N1)C(=O)NC(N)=N2)C1=CC=C(C=C1)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O
InChIKey: AUFGTPPARQZWDO-YUZLPWPTSA-L
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32)/p-2/t11?,13-/m0/s1
CHEBI:57454
Sample reactions for this molecule:
MTFMT formylates methionyl-tRNA
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF
MTHFD1L transforms 10-formyl-THF to HCOOH and THF
MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF
AICAR + 10-Formyl-THF => FAICAR + THF
GAR + 10-Formyl-THF => FGAR + THF