Meta-Biol : Molecules : 5,10-methenyltetrahydrofolate polyglutamate macromolecule

Molecule: 5,10-methenyltetrahydrofolate polyglutamate macromolecule

An ionic macromolecule consisting of (6R)-5,10-methenyltetrahydrofolate(2-) with an arbitrary number of glutamate residues attached as a polypeptide to the single existent one.

Synonyms for 5,10-methenyltetrahydrofolate polyglutamate macromolecule :

5,10-methenyltetrahydrofolate polyglutamate

Molecular Formula: C25H27N8O9.(C5H6NO3)n

Molecular wt: g/mole

Charge:

SMILES:

InChIKey:

CHEBI:65049

Sample reactions for this molecule:

5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+

MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG

MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG

5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate

MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG