Molecule: 5'-S-methyl-5'-thioadenosine

Adenosine with the hydroxy group at C-5' substituted with a methylthio (methylsulfanyl) group.
Synonyms for 5'-S-methyl-5'-thioadenosine :
5'-Deoxy-5'-(methylthio)adenosine
5'-Methylthioadenosine
5-Methylthioadenosine
9-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-9H-purin-6-amine
MTA
Methylthioadenosine
S-Methyl-5'-thioadenosine
S-methyl-5'-thioadenosine
Thiomethyladenosine
Molecular Formula: C11H15N5O3S
Molecular wt: 297.33470 g/mole
Charge: 0
SMILES: CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChIKey: WUUGFSXJNOTRMR-IOSLPCCCSA-N
InChI=1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
CHEBI:17509
Sample reactions for this molecule:
MTA is cleaved and phosphorylated
dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine
Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine
DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2
TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe)
TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248