Molecule: sphingoid base(1+)

A cationic sphingoid obtained by protonation of the amino group of any 2-amino-1,3-dihydroxysphingoid base.
Synonyms for sphingoid base(1+) :
2-amino-1,3-dihydroxysphingoid base(1+)
a sphingoid base
Molecular Formula: C3H9NO2R
Molecular wt: 91.10850 g/mole
Charge: +1
SMILES: [NH3+][C@@H](CO)[C@H](O)[*]
InChIKey:
CHEBI:84410
Sample reactions for this molecule:
ASAH2 hydrolyzes ceramide (plasma membrane)
ASAH1 hydrolyzes ceramide
ceramide + H2O => stearate + sphingosine [Golgi]
ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]
SPHK1 phosphorylates SPG to S1P
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]
SPHK1 phosphorylates sphingosine in response to E2 stimulation
SPHK2 phosphorylates SPG to S1P