Molecule: 17beta-estradiol

The 17beta-isomer of estradiol.
Synonyms for 17beta-estradiol :
(17beta)-estra-1,3,5(10)-triene-3,17-diol
17beta oestradiol
17beta-estra-1,3,5(10)-triene-3,17-diol
17beta-estradiol
17beta-oestradiol
ESTRADIOL
Estradiol
Estradiol-17beta
beta-Estradiol
cis-estradiol
Molecular Formula: C18H24O2
Molecular wt: 272.38200 g/mole
Charge: 0
SMILES: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21
InChIKey: VOXZDWNPVJITMN-ZBRFXRBCSA-N
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
CHEBI:16469
Estradiol
Sample reactions for this molecule:
beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
CYP19A1 hydroxylates TEST to EST17b
CYP1B1 4-hydroxylates EST17b
Defective CYP1B1 does not 4-hydroxylate EST17b
HSD17B11 dehydrogenates EST17b to E1
AKR1B15 reduces EST17b to E1
HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1)
HSD17B1 hydrogenates E1 to EST17b
HSD17B2 oxidises estradiol (E2) to estrone (E1)