Molecule: glutathione disulfide(2-)

A doubly-charged peptide anion arising from deprotonation of the four carboxy groups and protonation of the two amino groups of glutathione disulfide; major species at pH 7.3.
Synonyms for glutathione disulfide(2-) :
glutathione disulfide
glutathione disulfide dianion
Molecular Formula: C20H30N6O12S2
Molecular wt: 610.61500 g/mole
Charge: -2
SMILES: [NH3+][C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H]([NH3+])C([O-])=O)C(=O)NCC([O-])=O)C(=O)NCC([O-])=O)C([O-])=O
InChIKey: YPZRWBKMTBYPTK-BJDJZHNGSA-L
InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/p-2/t9-,10-,11-,12-/m0/s1
CHEBI:58297
Sample reactions for this molecule:
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)
Thiosulfate can transfer its sulfur atom to glutathione
GSTO dimers reduce DeHA to AscH-
15S-HpETE is reduced to 15S-HETE by GPX1/2/4
5S-HpETE is reduced to 5S-HETE by GPX1/2/4
12R-HpETE is reduced to 12R-HETE by GPX1/2/4
12S-HpETE is reduced to 12S-HETE by GPX1/2/4
GSSeH condenses with GSH to form H2Se and GSSG
SeO3(2-) combines with GSH to form GSSeSG and GSSG
GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O